Lamin B Receptor (LBR) Rabbit Polyclonal Antibody

CAT#: TA356483

LBR Antibody - middle region

Product Images

WB Suggested Anti-LBR Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: RPMI 8226 cell lysateLBR is supported by BioGPS gene expression data to be expressed in RPMI 8226

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  Host: Rabbit Target: LBR Positive control (+): RPMI-8226 (N12) Negative control (-): A549 (N03) Antibody concentration: 1ug/ml

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  LBR was immunoprecipitated from 2 mg HEK293 Whole Cell Lysate with TA356483 with 1:200 dilution. Western blot was performed using TA356483 at 1/1000 dilution. Lane 1: Control IP in HEK293 Whole Cell Lysate. Lane 2: LBR IP with TA356483 in HEK293 Whole Cell Lysate. Lane 3: Input of HEK293 Whole Cell Lysate.

Specifications

Product Data

• Applications: IP, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LBR
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
  Homology: Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%; Yeast: 77%; Zebrafish: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 71kDa
• Gene Name: lamin B receptor
• Database Link:
  NP_002287
  Entrez Gene 3930 Human
  UniProt ID Q14739
• Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
• Synonyms: DHCR14B; FLJ43126; LMN2R; MGC9041; PHA

Reference Data

• Protein Families: Druggable Genome, Transmembrane