LOX 1 (OLR1) Rabbit Polyclonal Antibody

CAT#: TA356496

OLR1 Antibody - N-terminal region

Product Images

WB Suggested Anti-OLR1 Antibody Titration: 2.5ug/ml Positive Control: Jurkat cell lysate

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OLR1
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 20kDa
• Gene Name: oxidized low density lipoprotein receptor 1
• Database Link:
  NP_001166103
  Entrez Gene 4973 Human
  UniProt ID P78380
• Background: OLR1 is a receptor protein which belongs to the C-type lectin superfamily. OLR1 binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of its gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease.
• Synonyms: CLEC8A; hLOX-1; LOX-1; LOX1; SCARE1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: PPAR signaling pathway