Transferrin Receptor 2 (TFR2) Rabbit Polyclonal Antibody

CAT#: TA356536

TFR2 Antibody - middle region

Product Images

WB Suggested Anti-TFR2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Hela cell lysate

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  Immunohistochemistry with Human Thymus lysate tissue at an antibody concentration of 5.0ug/ml using anti-TFR2 antibody (TA356536)

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFR2
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 89kDa
• Gene Name: transferrin receptor 2
• Database Link:
  NP_003218
  Entrez Gene 7036 Human
  UniProt ID Q9UP52
• Background: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Synonyms: HFE3; MGC126368; TFRC2

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane