alpha 2 Macroglobulin (A2M) Rabbit Polyclonal Antibody

CAT#: TA357558

A2M Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: A2M Antibody Dilution: 1.0ug/ml Sample Type: Human skin

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  Rabbit Anti-A2M Antibody Catalog Number: TA357558 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 161kDa
• Gene Name: alpha-2-macroglobulin
• Database Link:
  NP_000005
  Entrez Gene 2 Human
  UniProt ID P01023
• Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
• Synonyms: Alpha-2-M; alpha-2-macroglobulin; CPAMD5; DKFZp779B086; FWP007; S863-7

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades