Numb Rabbit Polyclonal Antibody

CAT#: TA357588

Numb Antibody - C-terminal region

Product Images

Numb antibody - C-terminal region (TA357588) validated by WB using Mouse Brain lysate at 1.0ug/ml.

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  Sample Type: 3. rat brain extract (80ug) Primary Antibody Dilution: 2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: 1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical ScienceÂ

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  Researcher: Dr. Yuzhi Chen, University of Arkansas for Medical Science Application: IHC Species+tissue/cell type: Human brain stem cells Primary antibody dilution: 1:500 Secondary antibody: Goat anti-rabbit Alexa-Fluor 594 Secondary antibody dilution: 1:1000

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 66kDa
• Gene Name: numb homolog (Drosophila)
• Database Link:
  NP_035079
  Entrez Gene 8650 HumanEntrez Gene 29419 RatEntrez Gene 18222 Mouse
  UniProt ID Q9QZS3-2
• Background: Numb plays a role in the process of neurogenesis. It is required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. It is not required for the proliferation of neural progenitor cells before the onset of neurogenesis. It is also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. It may also mediate local repair of brain ventricular wall damage.
• Synonyms: h-Numb; S171