APRIL (TNFSF13) Rabbit Polyclonal Antibody

CAT#: TA357780

TNFSF13 Antibody - middle region

Product Images

WB Suggested Anti-TNFSF13 Antibody Titration: 1.0 ug/ml Positive Control: HCT15 Whole CellTNFSF13 is strongly supported by BioGPS gene expression data to be expressed in Human HCT15 cells

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Goat, Horse, Human, Pig, Rabbit, Rat
  Homology: Cow: 91%; Dog: 86%; Goat: 79%; Horse: 86%; Human: 100%; Pig: 93%; Rabbit: 79%; Rat: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 16kDa
• Gene Name: tumor necrosis factor superfamily member 13
• Database Link:
  NP_003799
  Entrez Gene 8741 Human
  UniProt ID O75888
• Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
• Synonyms: APRIL; CD256; ligand; TALL-2; TALL2; TRDL-1; UNQ383/PRO715; ZTNF2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction