VPS4B Rabbit Polyclonal Antibody

CAT#: TA357925

VPS4B Antibody - N-terminal region

Product Images

WB Suggested Anti-VPS4B Antibody Titration: 1.0 ug/ml Positive Control: OVCAR-3 Whole CellVPS4B is supported by BioGPS gene expression data to be expressed in OVCAR3

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
  Homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Rabbit: 86%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 49kDa
• Gene Name: vacuolar protein sorting 4 homolog B
• Database Link:
  NP_004860
  Entrez Gene 9525 Human
  UniProt ID O75351
• Background: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
• Synonyms: MIG1; SKD1; SKD1B; VPS4-2; VPS42

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Endocytosis