G protein coupled receptor 30 (GPER1) Rabbit Polyclonal Antibody

CAT#: TA358122

GPER Antibody - C-terminal region

Product Images

WB Suggested Anti-GPER Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell

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  Host: Rabbit Target Name: GPER Sample Type: Human 721_B Antibody Dilution: 1.0ug/mlGPER1 is supported by BioGPS gene expression data to be expressed in 721_B

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  Host: Rabbit Target Name: GPER Sample Tissue: Human THP-1 Whole Cell Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rat
  Homology: Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 42kDa
• Gene Name: G protein-coupled estrogen receptor 1
• Database Link:
  NP_001091671
  Entrez Gene 2852 Human
  UniProt ID Q99527
• Background: This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane