CFHL1 (CFHR1) Rabbit Polyclonal Antibody

CAT#: TA358129

CFHR1 Antibody - N-terminal region

Product Images

WB Suggested Anti-CFHR1 Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human, Rat
  Homology: Human: 100%; Rat: 77%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 36kDa
• Gene Name: complement factor H related 1
• Database Link:
  NP_002104
  Entrez Gene 3078 Human
  UniProt ID Q03591
• Background: This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
• Synonyms: CFHL; CFHL1; CFHL1P; CFHR1P; FHR-1; FHR1; H36; H36-1; H36-2; HFL1; HFL2; MGC104329

Reference Data

• Protein Families: Secreted Protein