CD62L (SELL) Rabbit Polyclonal Antibody

CAT#: TA358322

SELL Antibody - C-terminal region

Product Images

WB Suggested Anti-SELL Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human, Pig
  Homology: Human: 100%; Pig: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 41kDa
• Gene Name: selectin L
• Database Link:
  NP_000646
  Entrez Gene 6402 Human
  UniProt ID P14151
• Background: This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: CD62L; gp90-MEL; hLHRc; LAM-1; LAM1; LECAM1; Leu-8; LEU8; LNHR; LSEL; Lyam-1; LYAM1; PLNHR; TQ1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)