CD82 Rabbit Polyclonal Antibody

CAT#: TA358408

CD82 Antibody - C-terminal region

Product Images

WB Suggested Anti-CD82 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human, Yeast
  Homology: Human: 100%; Yeast: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 29kDa
• Gene Name: CD82 molecule
• Database Link:
  NP_002222
  Entrez Gene 3732 Human
  UniProt ID P27701
• Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Synonyms: 4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; Tetraspanin-27; Tspan-27; TSPAN27

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: p53 signaling pathway