BAG1 Rabbit Polyclonal Antibody

CAT#: TA358442

BAG1 Antibody - N-terminal region

Product Images

WB Suggested Anti-BAG1 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole CellBAG1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Pig, Rabbit, Zebrafish
  Homology: Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Pig: 86%; Rabbit: 91%; Zebrafish: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 25kDa
• Gene Name: BCL2 associated athanogene 1
• Database Link:
  NP_001165886
  Entrez Gene 573 Human
  UniProt ID Q99933-4
• Background: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
• Synonyms: BAG-1; HAP; RAP46

Reference Data

• Protein Families: Druggable Genome