DIAPH1 Rabbit Polyclonal Antibody

CAT#: TA358568

DIAPH1 Antibody - C-terminal region

Product Images

WB Suggested Anti-DIAPH1 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole CellThere is BioGPS gene expression data showing that DIAPH1 is expressed in HepG2

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 85%; Dog: 100%; Human: 100%; Mouse: 93%; Pig: 92%; Rabbit: 86%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 141kDa
• Gene Name: diaphanous related formin 1
• Database Link:
  NP_005210
  Entrez Gene 1729 Human
  UniProt ID O60610
• Background: This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Synonyms: DFNA1; DIA1; DIAP1; DRF1; FLJ25265; hDIA1; LFHL1

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Focal adhesion, Regulation of actin cytoskeleton