FKBP51 (FKBP5) Rabbit Polyclonal Antibody

CAT#: TA362569

FKBP5 Antibody - middle region

Product Images

Host: Rabbit Target Name: FKBP5 Sample Tissue: Human HCT116 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FKBP5
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 50 kDa
• Gene Name: FK506 binding protein 5
• Database Link:
  NP_001139247.1
  Entrez Gene 2289 Human
  UniProt ID Q13451
• Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
• Synonyms: AIG6; FKBP-51; FKBP51; FKBP54; MGC111006; OTTHUMP00000016268; P54; PPIase; Ptg-10; rotamase