Phb2 Rabbit Polyclonal Antibody

CAT#: TA363157

PHB2 Antibody - middle region

Product Images

Host: Rabbit Target Name: PHB2 Sample Tissue: Mouse Liver lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse PHB2
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 33 kDa
• Gene Name: prohibitin 2
• Database Link:
  NP_031557.2
  UniProt ID O35129
• Background: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
• Synonyms: BAP; Bap37; BCAP37; D-prohibitin; MGC117268; p22; PNAS-141; REA