Lrrfip1 Rabbit Polyclonal Antibody

CAT#: TA363172

LRRFIP1 Antibody - middle region

Product Images

Host: Rabbit Target Name: LRRFIP1 Sample Tissue: Mouse Heart lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse LRRFIP1
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 52 kDa
• Gene Name: leucine rich repeat (in FLII) interacting protein 1
• Database Link:
  NP_001104781.1
  UniProt ID Q3UZ39-3
• Background: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity). Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).
• Synonyms: FLAP-1; FLIIAP1; GCF-2; GCF2; HUFI-1; MGC10947; MGC119738; MGC119739; TRIP