Corticotropin Releasing Factor (CRH) Rabbit Polyclonal Antibody

CAT#: TA363909

Rabbit polyclonal anti human / mouse / rat Corticotropin-Releasing Factor (CRF)

Product Images

Typical titration curve of CRF in a compeittive ELISA with this antibody

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against CRF and in immunohistochemistry (IHC). Other applications like FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe- His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln- Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2 coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: corticotropin releasing hormone
• Database Link:
  Entrez Gene 1392 Human
  UniProt ID P06850
• Background: Corticotropin-Releasing Factor (CRF, also known as Corticoliberin) is a 41 amino acid peptide hormone derived from the 196-amino acid preprohormone. It is secreted in the hypothalamus in response to stress, and stimulates both the synthesis and the secretion of adrenocorticotropic hormone (ACTH). CRF is also synthesized in peripheral tissues and placenta and it is known to suppress appetite and increase subjective feelings of anxiety. This antibody was generated by immunization of rabbits with CRF coupled to a carrier protein.
• Synonyms: CRF