ATG4C Rabbit Polyclonal Antibody

CAT#: TA364621

ATG4C rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Mouse heart tissue Primary antibody: TA364621 (ATG4C Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

• 

  Immunohistochemistry of paraffin-embedded Human brain tissue using TA364621 (ATG4C Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human brain tissue using TA364621 (ATG4C Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA364621 (ATG4C Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA364621 (ATG4C Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse heart tissue
  IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ATG4C
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 52 kDa
• Database Link:
  UniProt ID Q96DT6
• Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.