HNF1A Rabbit Polyclonal Antibody

CAT#: TA367401

HNF1A rabbit polyclonal antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Human kidney tissue, Rat liver tissue, Mouse liver tissue and A172 cell lysates
IHC: 25-100
Positive control: Human esophagus cancer
Predicted cell location: Nucleus
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human HNF1A
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Predicted Protein Size 67 kDa
Background The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.