TMPRSS11F Rabbit Polyclonal Antibody

CAT#: TA371569

TMPRSS11F rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: Human esophagus tissue Human thyroid cancer tissue Primary antibody: TA371569 (TMPRSS11F Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human esophagus and thyroid cancer tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TMPRSS11F
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 49 kDa
• Gene Name: transmembrane protease, serine 11F
• Database Link:
  Entrez Gene 389208 Human
  UniProt ID Q6ZWK6
• Background: TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
• Synonyms: FLJ16046; HATL4