Hsp22 (HSPB8) Rabbit Polyclonal Antibody

CAT#: TA377270

HSPB8/HSP22 Rabbit polyclonal Antibody


USD 220.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:200
IF,1:50 - 1:100
Reactivities Human, Mouse, Rat
Modifications Unmodified
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8/HSP22 (NP_055180.1).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 21kDa
Gene Name heat shock protein family B (small) member 8
Background The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.