CDT2 (DTL) Rabbit Polyclonal Antibody

CAT#: TA384120

CDT2 Rabbit polyclonal Antibody

Product Images

Western blot analysis of CDT2 expression in 293T cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/50-1/100
  ICC/IF: 1/50-1/100
  FC: 1/80
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human CDT2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 91kDa
• Gene Name: denticleless E3 ubiquitin protein ligase homolog
• Database Link:
  Entrez Gene 51514 Human
  UniProt ID Q9NZJ0
• Background: Swiss-Prot Acc.Q9NZJ0.Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).
• Synonyms: CDT2; CDW1; DCAF2; L2DTL; RAMP