EIF5A Rabbit Monoclonal Antibody [Clone ID: R09-3F9]

CAT#: TA384164

eIF5A Rabbit monoclonal Antibody

Product Images

Western blot detection of eIF5A in Jurkat cell lysates using eIF5A Rabbit mAb(1:1000 diluted).Predicted band size:17KDa.Observed band size:17KDa.

• 

  Western blot detection of eIF5A in Jurkat,THP-1,C6,3T3,Hela cell lysates using eIF5A Rabbit mAb(1:1000 diluted).Predicted band size:17KDa.Observed band size:17KDa.

• 

  Immunohistochemistry of eIF5A in paraffin-embedded Human breast cancer tissue using eIF5A Rabbit mAb at dilution 1/1

Specifications

Product Data

• Clone Name: R09-3F9
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/2000
  IHC: 1/20
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human eIF5A
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 17 kDa; Observed MW: 17 kDa
• Gene Name: eukaryotic translation initiation factor 5A
• Database Link:
  Entrez Gene 1984 Human
  UniProt ID P63241
• Background: Swiss-Prot Acc.P63241.mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
• Synonyms: eIF-4D; EIF-5A; eIF-5A-1; eIF-5A1; EIF5A1; eIF5AI; MGC99547; MGC104255