Islet 1 (ISL1) Rabbit Polyclonal Antibody

CAT#: TA384549

Islet 1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of Islet 1 expression in K562 cell lysate.

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: WB: 1/1000-1/2000
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Islet 1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 39kDa
• Gene Name: ISL LIM homeobox 1
• Database Link:
  Entrez Gene 3670 Human
  UniProt ID P61371
• Background: Swiss-Prot Acc.P61371.ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.
• Synonyms: Isl-1; islet-1; ISLET1