REA (PHB2) Rabbit Monoclonal Antibody [Clone ID: R01-5J9]

CAT#: TA384972

REA Rabbit monoclonal Antibody

Product Images

Western blot detection of REA in K562,Rat Brain,C6,3T3,Hela cell lysates using REA Rabbit mAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:33kDa.

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  Immunocytochemistry of REA(green) in Hela cells using REA Rabbit mAb at dilution 1/50, and DAPI(blue)

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  Immunohistochemistry of REA in paraffin-embedded Human colon cancer tissue using REA Rabbit mAb at dilution 1/5

Specifications

Product Data

• Clone Name: R01-5J9
• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/2000-1/10000
  IHC: 1/50
  ICC/IF: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human REA
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 33 kDa; Observed MW: 33 kDa
• Gene Name: prohibitin 2
• Database Link:
  Entrez Gene 11331 Human
  UniProt ID Q99623
• Background: Swiss-Prot Acc.Q99623.Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases . Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
• Synonyms: BAP; Bap37; BCAP37; D-prohibitin; MGC117268; p22; PNAS-141; REA