BIRC5 Mouse Monoclonal Antibody [Clone ID: OTI2D9]

CAT#: TA400024

Anti-BIRC5/Survivin mouse mAb, clone OTI2D9, Biotinylated


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USD 399.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI2D9
Applications WB
Recommended Dilution WB: 1:1000
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BIRC5 (NP_001159) produced in HEK293T cell.
Formulation PBS (pH7.4) containing 50% glycerol, 0.1% BSA and 0.02% NaN3
Concentration 0.5 mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 16.2 kDa
Gene Name baculoviral IAP repeat containing 5
Background This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Synonyms API4; EPR-1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Pathways in cancer

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