MYD88 Mouse Monoclonal Antibody [Clone ID: OTI1B4]

CAT#: TA502104S

MYD88 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)

Size: 30 ul 100 ul


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USD 159.00

In Stock*

Size
    • 30 ul

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Specifications

Product Data
Clone Name OTI1B4
Applications FC, IF, WB
Recommended Dilution WB 1:2000, IF 1:100, FLOW 1:100
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 33.1 kDa
Gene Name MYD88 innate immune signal transduction adaptor
Background This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms MYD88D
Reference Data
Protein Families Druggable Genome
Protein Pathways Apoptosis, Toll-like receptor signaling pathway

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