IKB zeta (NFKBIZ) Mouse Monoclonal Antibody (PE conjugated) [Clone ID: OTI1E8]

CAT#: TA502768HM

NFKBIZ mouse monoclonal antibody, clone 1E8, PE conjugated


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USD 399.00

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Size
    • 100 ul

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Specifications

Product Data
Clone Name OTI1E8
Applications FC, WB
Recommended Dilution WB 1:500, FLOW 1:100
Reactivities Human, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation PE
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 77.9 kDa
Gene Name NFKB inhibitor zeta
Background This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms IKBZ; INAP; MAIL
Reference Data
Protein Families Druggable Genome

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