APBB3 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5G3]

CAT#: TA503752AM

APBB3 mouse monoclonal antibody, clone OTI5G3 (formerly 5G3), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APBB3 (RC219752, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APBB3. Positive lysates LY408843 (100ug) and LC408843 (20ug) can be purchased separately from OriGene.

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  Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

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  Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

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  Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

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  Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

• Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

• Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

• Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

• Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-APBB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503752)

• HEK293T cells transfected with either RC219752 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-APBB3 antibody (TA503752), and then analyzed by flow cytometry.

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Specifications

Product Data

• Clone Name: OTI5G3
• Applications: FC, IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:150, FLOW 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinan protein of human APBB3(NP_573419) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52.4 kDa
• Gene Name: amyloid beta precursor protein binding family B member 3
• Database Link:
  NP_573419
  Entrez Gene 117026 RatEntrez Gene 225372 MouseEntrez Gene 10307 Human
  UniProt ID O95704
• Background: The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: FE65L2; SRA