Iduronate 2 sulfatase (IDS) Mouse Monoclonal Antibody [Clone ID: OTI3B10]

CAT#: TA504276

IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10)

Size: 30 ul 100 ul

Formulation: Standard Carrier Free


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USD 379.00

In Stock*

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI3B10
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivities Human, Mouse
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IDS(NP_000193) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.79 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 59.2 kDa
Gene Name iduronate 2-sulfatase
Background Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq]
Synonyms MPS2; SIDS
Reference Data
Protein Families Druggable Genome
Protein Pathways Glycosaminoglycan degradation, Lysosome, Metabolic pathways

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