CDK2AP1 Rabbit Polyclonal Antibody

CAT#: TA590189

Rabbit Polyclonal CDK2AP1 Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDK2AP1 (RC204442, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDK2. Positive lysates LY401472 (100ug) and LC401472 (20ug) can be purchased separately from OriGene.

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  ELISA: CDK2AP1 Antibody

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  Immunohistochemical staining of human lateral ventricle shows strong positivity in Astrocytes.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB 1:20000, ELISA 1:100-1:2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DNA immunization. This antibody is specific for the entire range of the target protein.
• Formulation: 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
• Concentration: 0.95109 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cyclin dependent kinase 2 associated protein 1
• Database Link:
  NP_004633
  Entrez Gene 8099 Human
  UniProt ID O14519
• Background: The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
• Synonyms: doc-1; DOC1; DORC1; p12DOC-1; ST19
• Note: This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT