Galectin 3 (LGALS3) Mouse Monoclonal Capture Antibody [Clone ID: OTI1A3]

CAT#: TA600570

Galectin-3 mouse monoclonal antibody, clone OTI1A3

Specifications

Product Data

• Clone Name: OTI1A3
• Applications: ELISA
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human LGALS3(NP_002297) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 26.2 kDa
• Gene Name: galectin 3
• Database Link:
  NP_002297
  Entrez Gene 3958 Human
  UniProt ID P17931
• Background: Galectin-3 is a protein encoded by the LGALS3 gene (in human). It is a member of the lectin family and has an affinity for beta-galactosides. Galectin-3 is involved in many biological processes such as cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis. It has been demonstrated that galectin-3 involves in cancer, inflammation, fibrosis, heart disease, and stroke. Galectin-3 is upregulated in cases of liver fibrosis, renal fibrosis, and idiopathic pulmonary fibrosis, and elevated levels of galectin-3 are significantly associated with higher risk of death in both acute decompensated heart failure and chronic heart failure populations. In addition, galectin-3 is increasingly being used as a diagnostic and prognostic marker for different cancers.
• Synonyms: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2

Reference Data

• Protein Families: Secreted Protein