SETD2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3G8]

CAT#: TA804268AM

SETD2 mouse monoclonal antibody, clone OTI3G8 (formerly 3G8), Biotinylated


USD 420.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI3G8
Applications WB
Recommended Dilution WB 1:200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1787-2144 of human SETD2 (NP_054878) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name SET domain containing 2
Background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug
Synonyms HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; p231HBP; SET2
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysine degradation

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.