DCC Mouse Monoclonal Antibody [Clone ID: OTI4A1]

CAT#: TA804515S

DCC mouse monoclonal antibody, clone OTI4A1 (formerly 4A1)

Size: 30 ul 100 ul


  View other "OTI4A1" antibodies (2)

USD 159.00

2 Days*

Size
    • 30 ul

Product Images

Frequently bought together (3)
Mouse monoclonal anti-GAPDH antibody, clone OTI2D9 (formerly 2D9), loading control
    • 30 ul

USD 159.00


DCC HEK293T cell transient overexpression lysate (as WB positive control)
    • 20 ug

USD 187.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Specifications

Product Data
Clone Name OTI4A1
Applications WB
Recommended Dilution WB 1:200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human DCC (NP_005206) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 158.3 kDa
Gene Name DCC netrin 1 receptor
Background This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
Synonyms CRC18; CRCR1; IGDCC1; MRMV1; NTN1R1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Axon guidance, Colorectal cancer, Pathways in cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.