ROR1 Mouse Monoclonal Antibody [Clone ID: OTI3D11]

CAT#: TA806826

ROR1 mouse monoclonal antibody, clone OTI3D11 (formerly 3D11)

Product Images

Figure A, Western blot analysis of overexpressed lysates(15ug per lane) from HEK293T cells transfected with empty plasmid (PS100001, lane 1) , human ROR1 plasmid (RC214967, lane 2), mouse ROR1 plasmid (MR224803, lane 3), rat ROR1 plasmid (RR214709, lane 4), using anti-ROR1 antibody TA806826 (1:500). Figure B, Western blot analysis of the same samples as figure A with anti-DDK antibody (TA180144, 1:1000)

Specifications

Product Data

• Clone Name: OTI3D11
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human ROR1 (NP_005003) produced in HEK293T cell.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 104.1 kDa
• Gene Name: receptor tyrosine kinase-like orphan receptor 1
• Database Link:
  NP_005003
  Entrez Gene 4919 Human
  UniProt ID Q01973
• Background: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun
• Synonyms: dJ537F10.1; NTRKR1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane