FOLR3 Mouse Monoclonal Antibody [Clone ID: OTI7E10]

CAT#: TA811544S

FOLR3 mouse monoclonal antibody,clone OTI7E10

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOLR3 (RC212963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOLR3 (1:2000).

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  Immunohistochemical staining of paraffin-embedded Human appendix tissue within the normal limits using anti-FOLR3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA811544) (1:2000)

Specifications

Product Data

• Clone Name: OTI7E10
• Applications: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human FOLR3 (NP_000795) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: folate receptor 3 (gamma)
• Database Link:
  NP_000795
  Entrez Gene 2352 Human
  UniProt ID P41439
• Background: This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
• Synonyms: FR-G; FR-gamma; gamma-hFR

Reference Data

• Protein Families: Druggable Genome, Secreted Protein