L1CAM Mouse Monoclonal Antibody [Clone ID: UMAB48]
Other products for "L1CAM"
Specifications
Product Data | |
Clone Name | UMAB48 |
Applications | IF, IHC, WB |
Recommended Dilution | IHC 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 137.8 kDa |
Gene Name | Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA. |
Database Link | |
Background | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008] |
Synonyms | CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Axon guidance, Cell adhesion molecules (CAMs) |
Documents
Product Manuals |
FAQs |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
UM500044CF | Carrier-free (BSA/glycerol-free) L1CAM mouse monoclonal antibody, clone UMAB48 |
USD 528.00 |
|
UM570044 | L1CAM mouse monoclonal antibody, clone UMAB48 |
USD 180.00 |
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