PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: UMAB222]

CAT#: UM800114

PD-1 (PDCD1) mouse monoclonal antibody, clone UMAB222

Size: 30 ul 100 ul


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USD 468.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Clone Name UMAB222
Applications 10k-ChIP, FC, NEUT, WB
Recommended Dilution IHC 1:100, FLOW 1:50
Reactivities Human, Mouse
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 29.2 kDa
Gene Name Homo sapiens programmed cell death 1 (PDCD1), mRNA.
Background This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Synonyms CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), T cell receptor signaling pathway

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