PAX2 Rabbit Monoclonal Antibody [Clone ID: UMAB301]

CAT#: UM900006

PAX2 Rabbit monoclonal antibody,clone UMAB301

Product Images

IHC staining of FFPE human kidney tissue with in the normal limits using anti-PAX2 rabbit monoclonal antibody (UM900006) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 (B06C-50) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

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  IHC staining of FFPE human renal cancer tissue using anti-PAX2 rabbit monoclonal antibody (UM900006) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 (B06C-50) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

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  IHC staining of FFPE human endometrial carcinoma tissue using anti-PAX2 rabbit monoclonal antibody (UM900006) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 (B06C-50) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

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  IHC staining of FFPE human fallopian tube tissue with in the normal limits using anti-PAX2 rabbit monoclonal antibody (UM900006) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 9.0 (B06C-50) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

Specifications

Product Data

• Clone Name: UMAB301
• Applications: IHC
• Recommended Dilution: IHC 1:250
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment of human PAX2 (NP_003978) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1.00mg/ml
• Purification: Purified from cell culture supernatant by affinity chromatography(protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 44.5 kDa
• Gene Name: Homo sapiens paired box 2 (PAX2), transcript variant a, mRNA.
• Database Link:
  NP_003978
  Entrez Gene 5076 Human
  UniProt ID Q02962
• Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
• Synonyms: FSGS7; PAPRS

Reference Data

• Protein Families: Druggable Genome