Mortality Factor 4 like 2 (MORF4L2) (NM_012286) Human 3' UTR Clone

CAT#: SC208805

3`UTR clone of mortality factor 4 like 2 (MORF4L2) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: MORF4L2
• Synonyms: MORFL2; MRGX
• ACCN: NM_012286
• Insert Size: 676
• Sequence Data:
  Insert Sequence

  >SC208805 3'UTR clone of NM_012286
  The sequence shown below is from the reference sequence of NM_012286. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAAAGTGGCTTCTGCTGAGTACCACCGCAAAGCCCTGTGAGCGTCTACAGACAGCTCACCATTTTTGTCC
  TGTATCTGTAAACACTTTTTGTTCTTAGTCTTTTTCTTGTAAAATTGATGTTCTTTAAAATCGTTAATGT
  ATAACAGGGCTTATGTTTCAGTTTGTTTTCCGTTCTGTTTTAAACAGAAAATAAAAGGAGTGTAAGCTCC
  TTTTCTCATTTCAAAGTTGCTACCAGTGTATGCAGTAATTAGAACAAAGAAGAAACATTCAGTAGAACAT
  TTTATTGCCTAGTTGACAACATTGCTTGAATGCTGGTGGTTCCTATCCCTTTGACACTACACAATTTTCT
  AATATGTGTTAATGCTATGTGACAAAACGCCCTGATTCCTAGTGCCAAAGGTTCAACTTAATGTATATAC
  CTGAAAACCCATGCATTTGTGCTCTTTTTTTTTTTTTATGGTGCTTGAAGTAAAACAGCCCATCCTCTGC
  AAGTCCATCTATGTTGTTCTTAGGCATTCTATCTTTGCTCAAATTGTTGAAGGATGGTGATTTGTTTCAT
  GGTTTTTGTATTTGAGTCTAATGCACGTTCTAACATGATAGAGGCAATGCATTATTGTGTAGCCACGGTT
  TTCTGGAAAAGTTGATATTTTAGGAATTGTATTTCAGATCTTAAAT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_012286.2
• Summary: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. [UniProtKB/Swiss-Prot Function]
• Locus ID: 9643