MVK (NM_001114185) Human 3' UTR Clone

CAT#: SC209092

3`UTR clone of mevalonate kinase (MVK) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: MVK
• Synonyms: LRBP; MK; MVLK; POROK3
• ACCN: NM_001114185
• Insert Size: 697 bp
• Sequence Data:
  Insert Sequence

  >SC209092 3'UTR clone of NM_001114185
  The sequence shown below is from the reference sequence of NM_001114185. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GACAGCCGAGTCCAGCAAGCCCTGGATGGCCTCTGAGAGGAGCCCACGACACTGCAGCCCCACCCAGATG
  CCCCTTTCTGGATTATTCTGGGGGCTGCAGTTCGACTCTGTGCTGGCCAGCGAGCGCCCAGCTCCTGACA
  CTGCTGGAGAGGCCCCAGCCGCTTGGCGATGCCAGCCAAGCTCTGCAGTCCCAGCGGTGGGACCTAGGGA
  GGCATGGTCTGCCCTCTGCATCCTCTGGAGCCAGCCGAGCAGGAGGCCTAGGAGGGTCCTCTGAGACTCC
  AGACCTGAGGCGAGAAGGGCTGCTTCCCTGAAGCTCCCACAGTCCCATCTGCTTCAGGCCCCCGCCTTGG
  CCTGTGTTCTTCCTGGCCGCCTGGGTCCAATGCTCAGGTGCTGGGGCCTGGTTCCCGGAGAAGTGTGCCT
  TCTCTCTCCCTTTTCAGGGACCGCCCCCTGTCTCTCAGGGCCAGGCCTCTCCCTCCTCCAGGAAGCCTTC
  CCCTACCCCTTGTCGCCCCTCCCTCCCAGAGCACCTGCTGTCTGGGTGGCTCACTCAGCACTTGGTGTGG
  CCTTCCCTTCTACCTAGCGGGATGGGGCTCCCCCAGGGGCTGTCCCGGAGGCGGTGGGCCTGGTTAAATA
  AGGCAGGGTTTATATGCACTTTCTTCCGATCTGTACCTGAGAGGTTTGTGGAAAAGATGGCAAATGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001114185.1
• Summary: 'This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]'
• Locus ID: 4598