FOXP2 (NM_014491) Human 3' UTR Clone

CAT#: SC212500

3`UTR clone of forkhead box P2 (FOXP2) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: FOXP2
• Synonyms: CAGH44; SPCH1; TNRC10
• ACCN: NM_014491
• Insert Size: 1140
• Sequence Data:
  Insert Sequence

  >SC212500 3'UTR clone of NM_014491
  The sequence shown below is from the reference sequence of NM_014491. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AAGAGCCTTTATCTGAAGATCTGGAATGAGAACTGACTTGTGAAACCTCAGCGTGAAGGGACATATCACT
  GACCTTCATAACCACTCCACAACCATGAATATTTGACAAATTTTTACTGTGACTATTTATTAAGCATGGA
  TAAAGGAGACAGCCCTAAAGGAACTTACTAAGCCAGCCCTTTGGGATTCAGTACCAACAGGCAAATTGCT
  TGTTTTCTTCTTCTTCTTCTTCTTTTTTTTTTTTTTTTTAGAAAAAAAGACAAAAACTGATTTTCTTGAA
  AAAAAAAAATGAACTGTTCTTTCTATAATGGCTTTGCCCATTTAAAAAATGTGGCTCTTAAGGGTTCATG
  AAATGACTGAATATGAGGATACATGTCCTGTAGAAAGCAAATGCGCCTCATATACTGCCAAAAATAGTGT
  TAGTTTCATTAATGTGAATTTTCCAGCATTCAGTAGTTGTAATGTTAGAAACAATTGCTGGTCAAGTTCA
  ACTTGTTGCTATTGTTTTTAATTTGCACAGGAGTAGTATCAGAAATTAGTGTCACTGCTTGTATCTAGCT
  GAATTTTAAACAACAGAACATTAGTTTTTTATGTTGGTGCCACCAACTGTAAATGACATAAGTTAGTTAT
  TACAAAACACAGTAATTAGACTGTTGCAACCATCTAAAACCTTAGGCTTCCAGTCTGTGCTGTTAGTGTT
  AAGATGTAAAGTGCAATCCTAAGCTAACATTATCTGTGCAAGCACCATAGAAACATTTGCATATCTGCAT
  AGATCTTACAACTGTACTCTTTACCTCCTTGTGATAAAGCTTTGTCTACCTGCAAACACAGTCAAAGGCT
  ACAGCTGCAAACCAAAGCCAACTCTAACCATGGCCAAGAGCTCAAGGACAGAAGCAGCCACATGCTTTGG
  TCAGCCTTCTGTAACTTCAATTAGTACAAAGGAACCTTTTCCATGAACTACCTGCTGTTTTCTGATGACC
  TCTGGGATCTTTTCATTTAGCCCTAAACAAAGAAACAAATATGACAAAAACCACAACTAAAAAATGTTAA
  TTCAGTCACAGAGTAATCTTCTGAGGCCAAAAGTCCATCTAAATGCAATGAAGATTTGCTTTCATTAAAG
  ACAGAGGTGAGGACAAAATC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_014491.2
• Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
• Locus ID: 93986