SH2D1A (NM_001114937) Human 3' UTR Clone

CAT#: SC216406

3`UTR clone of SH2 domain protein 1A (SH2D1A) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: SH2D1A
• Synonyms: DSHP; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; XLP; XLPD; XLPD1
• ACCN: NM_001114937
• Insert Size: 1791 bp
• Sequence Data:
  Insert Sequence

  >SC216406 3'UTR clone of NM_001114937
  The sequence shown below is from the reference sequence of NM_001114937. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TGATGTCTGCCTGAAAGCCCCATGAAGAAAAATAAAACACCTTGTACTTTATTTTCTATAATTTAAATAT
  ATGCTAAGTCTTATATATTGTAGATAATACAGTTCGGTGAGCTACAAATGCATTTCTAAAGCCATTGTAG
  TCCTGTAATGGAAGCATCTAGCATGTCGTCAAAGCTGAAATGGACTTTTGTACATAGTGAGGAGCTTTGA
  AACGAGGATTGGGAAAAAGTAATTCCGTAGGTTATTTTCAGTTATTATATTTACAAATGGGAAACAAAAG
  GATAATGAATACTTTATAAAGGATTAATGTCAATTCTTGCCAAATATAAATAAAAATAATCCTCAGTTTT
  TGTGAAAAGCTCCATTTTTAGTGAAATATTATTTTATAGCTACTAATTTTAAAATGTCTTGCTTGATTGT
  ATGGTGGGAAGTTGGCTGGTGTCCCTTGTCTTTGCCAAGTTCTCCACTAGCTATGGTGTCATAGGCTCTT
  TTGGGATTTTTGAAGCTGTATACTGTGTGCTAAAACAAGCACTAAACAAAGAGTGAAGGATTTATGTTTA
  ATTCTGAAAGCAACCTTCTTGCCTAGTGTTCTGATATTGGACAGTAAAATCCACAGACCAACCTGGAGTT
  GAAAATCTTATAATTTAAAATATGCTCTAAACATGTTTATCGTATTTGATGCTACAGGATTTGAAATTGT
  ATTACAAATCCAATGAAATGAGTTTTTCTTTTCATTTACCTCTGCCCCAGTTGTTTCTACTACATGGAAG
  ACCTCATTTTGAAGGGAAATTTCAGCAGCTGCAGCTCATGAGTAACTGATTTGTAACAAGCCTCCTTTTA
  AAGTAACCCTACAAAACCACTGGAAAGTTTATGGTTGTATTATTTTTTAAAAAAATTCCAAGTGATTGAA
  ACCTACACGAGATACAGAATTTTATGCGGCATTTTCTTCTCACATTTATATTTTTGTGATTTTGTGATTG
  ATTATATGTCACTTTGCTACAGGGCTCACAGAATTCATTCACTCAACAAACATAATAGGGCGCTGAGGGC
  ATAGAAGTAAAAACACCTGGTCCCTGCTCTCAGTTCACTGTCTTGTTGGACGAGAAAACAATAACGATAA
  AAGACAGTGAAAGAAAATAACGATAAAAGACAGTGAAAGAAAATAACAATAAAAGACAAGGAAAAAATAA
  CAATGAAAGTTGATAAGTACATGATAAGCGAGGTTCCCCGTGTGTAGGTAGATCTGGTCTTTAGAGGCAG
  ATAGATAGGTCAGTGCAAATACTCTGGTCCATGGGCCATATGAAAAGGCTAAGCTTCACTGTAAAATAAT
  AACTGGGAATTCTGGATTGTGTATGGGTGTTGGTGAACTTGGTTTTAATTAGTGAACTGCTGAGAGACAG
  AGCTATTCTCCATGTACTGGCAAGACCTGATTTCTGAGCATTTAATATGGATGCCGTGGGAGTACAAAAG
  TGGAGTGTGGCCTGAGTAATGCATTATGGGTGGTTTACCATTTCTTGAGGTAAAAGCATCACATGAACTT
  GTAAAGGAATTTAAAAATCCTACTTTCATAATAAGTTGCATAGGTTTAATAATTTTTAATTATATGGCTT
  GAGTTTAAATTGTAATAGGCGTAACTAATTTTAACTCTATAATGTGTTCATTCTGGAATAATCCTAAACA
  TATGAATTATGTTTGCATGTTCACTTCCAAGAGCCTTTTTTTGAAAAAAAGCTTTTTTTGAATCATCAAG
  TCTTTCACATTTAAATAAAGTGTTTGAAAGCTTTATTTACC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001114937.1
• Summary: 'This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
• Locus ID: 4068