Fkbp1a (NM_008019) Mouse Untagged Clone

CAT#: MC200170

Fkbp1a (untagged) - Mouse FK506 binding protein 1a (Fkbp1a), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fkbp1a
• Synonyms: Fkbp; Fkbp1; FKBP12
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004671 sequence for NM_008019
  CTCCGGCTCCACGCCGCCCGTCGCGCCGCCACCCGCGTCCTTTTCCTCCTCCTCCGCCAACGCCGCCGCC GCCGCCGCCGCCATGGGAGTGCAGGTGGAGACCATCTCTCCTGGAGACGGGCGCACCTTCCCAAAGCGCG GCCAGACCTGCGTGGTGCACTACACGGGGATGCTTGAAGATGGAAAGAAATTTGATTCCTCTCGGGACAG AAACAAGCCTTTTAAGTTTACACTAGGCAAGCAGGAGGTGATCCGAGGCTGGGAGGAAGGGGTAGCCCAG ATGAGTGTGGGTCAGAGAGCCAAACTGATAATCTCCTCAGACTATGCCTATGGAGCCACCGGGCACCCAG GCATCATCCCACCACATGCCACTCTTGTTTTTGATGTGGAGCTTCTAAAACTGGAATGACAGAAGTGGCC TCCTCCCTTAGCTCTGCACGTGGATCTGCCATGGAGGAATCTGGTACCTCCAGATGGGTGCACATGAATC CATGGGGAGCTCTTCCTGACGTCCCACCACCCTTTGTATAGACACCTACCCGACTGAATGTGTTCCGTCA CTCAGCTTTGCTTCGGACACCTCCATGTCCTCTTCCCCCCTCTGTATGTGTGTTGACCTAAACTATATGC CATAAACCTCAAGTTACTTTATTTTGGGGTGAAGACTCAGTTTCTGTTTCAGATCTAAGTTTCCAATGAA GTATATTGTCAAGTGTTAACAGCACAAGCGATGGGTTAACTTAGAATAGAAATTGGTGTTGGGGGGGGAT TTGCAAGAATTTTTATTTTATTTTATTTTAATTTTTTGGATGAAAATTTTATCTATTATATATTAAGACA TTCTGCTGCTGTGCTGCAAAGCCATAGCAGATTCGAGATGCTGTTGAGGGCTGGATTTTTCTCTAGTGAG GGAGGTCCTGTTAAACTGAAAGCCCTACCCAAACTGAGGTGGGAAGGAAGCGGGGGAGAGAGCCTTGGCT TCTGACAGTCCTTCCACCTTCTGAAACTAGCTGCCTTTTAAAGCAGATCCCTTCACTGCTATGTTGGACA CTACAGTATCTGTCCCTGGGTTGGCAGAGACTTGAAAGCCTTTGTGACCTGGCTTAATTTGTTTTTCATC CTATGGTTTTTCTAATGGATTTTCTGGACTTTTGTAATCTTGTAACTATTCAAGCTCCACTTTCTAAATT TTAAGAACTTCAGTGGAAAGTTTAAATTGAAGGTGCTGTTTGTAGACTCACCACCCAACGGACGCCCAGC CACCACGGCAAATCCTTGAGTGTTCTCTAAGAATACGATGCTGGTCATCACAGCTTCAGCATCTCCTGGG TTTTGATGCTTGGCTCTTTGCTGATCTTGGCTTCCTGGCTTTTCCTCCTTCAGTTCCTTCTCACCCTCTG CTGTCCTTGTGTAGTGATTTGGTGAGAGAAAGCTTTTGTCCCCTGCCCTCTGCACTACATATGCGGTTCA AGTTTTATTATTGCAATAAAAGTGCTTTATGCTGGCTTTTCTCAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_008019
• ORF Size: 327 bp
• Insert Size: 327
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC004671, AAH04671
• RefSeq Size: 1529
• RefSeq ORF: 327
• Locus ID: 14225
• Gene Summary: This gene is a member of the immunophilin family. The encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and is associated with immunoregulation, protein folding, receptor signaling, protein trafficking and T-cell activation. It may modulate the calcium release activity of the ryanodine receptor Ryr1. It also interacts with the type I TGF-beta receptor. Disruption of this gene in mouse causes severe ventricular defects. Pseudogenes of this gene have been defined on chromosomes 4, 10, 14, and 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 2 both encode the same isoform (1).