Gzmb (NM_013542) Mouse Untagged Clone

CAT#: MC200360

Gzmb (untagged) - Mouse granzyme B (Gzmb), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gzmb
• Synonyms: AI553453; CCP-1/C11; CCP1; Ctla-1; Ctla1; GZB
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC002085 sequence for NM_013542
  GGGGGTACAAGGTCACAGAGCCCCCTCTGCCTTCTTCCTCTCCTAGAGGTTAAAAGAGAGCAAGGACAAC ACTCTTGACGCTGGGACCTAGGCGGCCTTCCGGGGAAGATGAAGATCCTCCTGCTACTGCTGACCTTGTC TCTGGCCTCCAGGACAAAGGCAGGGGAGATCATCGGGGGACATGAAGTCAAGCCCCACTCTCGACCCTAC ATGGCCTTACTTTCGATCAAGGATCAGCAGCCTGAGGCGATATGTGGGGGCTTCCTTATTCGAGAGGACT TTGTGCTGACTGCTGCTCACTGTGAAGGAAGTATAATAAATGTCACTTTGGGGGCCCACAACATCAAAGA ACAGGAGAAGACCCAGCAAGTCATCCCTATGGTAAAATGCATTCCCCACCCAGACTATAATCCTAAGACA TTCTCCAATGACATCATGCTGCTAAAGCTGAAGAGTAAGGCCAAGAGGACTAGAGCTGTGAGGCCCCTCA ACCTGCCCAGGCGCAATGTCAATGTGAAGCCAGGAGATGTGTGCTATGTGGCTGGTTGGGGAAGGATGGC CCCAATGGGCAAATACTCAAACACGCTACAAGAGGTTGAGCTGACAGTACAGAAGGATCGGGAGTGTGAG TCCTACTTTAAAAATCGTTACAACAAAACCAATCAGATATGTGCGGGGGACCCAAAGACCAAACGTGCTT CCTTTCGGGGGGATTCTGGAGGCCCGCTTGTGTGTAAAAAAGTGGCTGCAGGCATAGTTTCCTATGGATA TAAGGATGGTTCACCTCCACGTGCTTTCACCAAAGTCTCGAGTTTCTTATCCTGGATAAAGAAAACAATG AAAAGCAGCTAACTACAGAAGCAACATGGATCCTGCTCTGATTACCCATCGTCCCTAGAGCTGAGTCCAG GATTGCTCTAGGACAGGTGGCAGGATCTGAATAAAGGACTGCAAAGACTGGCTTCATGTCCATTCACAAG GACCAGCTCTGTCCTTGGCAGGCCAATGGAACACCTCTTCTGCCACCATGCTGTGACAACCCAACTGACA TCTTCCTATGGAAGTTTGCCCTCTCCACAAAAGAAGTAGAATGTTTGCATTGGAGCTGGGCATGCTCTGC TTCCCCTCAGTGCCCCGAGAATGTTATCTAATGCTAGTCATCATTAATAGCTCCCTACAGAACTTTCATA CAGTTGCACCCAAGTTGCTGATGTGTTCTCTAGAATAGAGCAAGAAATAGTAAACAGAATTCCTTTTGCC TCTCTGTACTATTTTCCCCCAAATACCAAGATTTGTATGTTTTATAAAGCTAATTTCCTTATCAAATGAC ATCTTTTAATTTTTACATTAATGGCTTATTTTCAAGGTACAACCTGATTTTTTTATGGACAAAAATGATG TAAAATCAAATAAAACTAATTAATATATCCATTAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_013542
• ORF Size: 744 bp
• Insert Size: 744
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC002085, AAH02085
• RefSeq Size: 1452
• RefSeq ORF: 744
• Locus ID: 14939
• Gene Summary: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]