Casp8 (NM_009812) Mouse Untagged Clone

CAT#: MC200404

Casp8 (untagged) - Mouse caspase 8 (Casp8), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Casp8
• Synonyms: CASP-8; FLICE; MACH; Mch5
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC006737 sequence for NM_009812
  GCAGCCTATGGCCTCTAGGGCTGGCACCAGGATGCCACCTCTAATGATTAACTCAAACGCCTCTAAACAT TCGGAGGCATTTCTGTCCCCTATGCCCTAGTTCTCTCAGTTGTCTTTCATTCTGACTTCGGTGCTTAAAA GTCCAGCTTCTCGGAATCGGTAGCAAACCTCTGTGAGCCGGCGTGGAACAGGAAGTGAGTACAGTTCTGG GGAGCGCCGGCCCGGGCTGGAGGCTCGGAAAGCCCAAGCCAGCGGAGGCCTCGCCCGAGCTGGAGTTGTG ACCGGCGCGGCAGGTACTCGGCCACAGGTTACAGCTCTTCTACCTCTTGATAAGAATGGATTTCCAGAGT TGTCTTTATGCTATTGCTGAAGAACTGGGCAGTGAAGACCTGGCTGCCCTCAAGTTCCTGTGCTTGGACT ACATCCCACACAAGAAGCAGGAGACCATCGAGGATGCCCAGAAGCTATTTCTGAGGCTGCGGGAAAAGGG GATGTTGGAGGAAGGCAATCTGTCTTTCCTGAAAGAGCTGCTTTTCCACATCAGTCGGTGGGACCTGCTG GTCAACTTCCTAGACTGCAACCGAGAGGAGATGGTGAGAGAGCTGCGGGATCCAGACAATGCCCAGATTT CTCCCTACAGGGTCATGCTCTTTAAGCTCTCAGAAGAAGTGAGCGAGTTGGAATTGAGATCTTTTAAGTT CCTTTTGAACAATGAGATCCCCAAATGTAAGCTGGAAGATGACTTGAGCCTGCTTGAAATTTTTGTAGAA ATGGAGAAGAGGACCATGCTGGCAGAAAATAACTTGGAAACCCTAAAATCAATCTGTGACCAGGTCAACA AGAGCCTGCTGGGGAAGATCGAGGATTATGAAAGATCAAGCACAGAGAGAAGAATGAGCCTTGAAGGAAG GGAAGAGTTGCCACCTTCAGTTTTGGATGAGATGAGCCTCAAAATGGCGGAACTGTGTGACTCGCCAAGA GAACAAGACAGTGAGTCACGGACTTCAGACAAAGTTTACCAAATGAAGAACAAACCTCGGGGATACTGTC TGATCATCAACAATCATGATTTCAGCAAGGCCCGGGAAGACATAACCCAACTCCGAAAAATGAAGGACAG AAAAGGAACAGACTGTGATAAAGAGGCTCTGAGTAAGACCTTTAAGGAGCTTCATTTTGAGATAGTATCT TACGACGACTGCACTGCAAATGAAATCCACGAGATTCTAGAAGGCTACCAAAGCGCAGACCACAAGAACA AAGACTGCTTCATCTGCTGTATCCTATCCCACGGTGACAAGGGTGTCGTCTATGGAACGGATGGGAAGGA GGCCTCCATCTATGACCTGACATCTTACTTCACTGGTTCAAAGTGCCCTTCCCTGTCTGGGAAACCCAAG ATCTTTTTCATTCAGGCTTGCCAAGGAAGTAACTTCCAGAAAGGAGTGCCTGATGAGGCAGGCTTCGAGC AACAGAACCACACTTTAGAAGTGGATTCATCATCTCACAAGAACTATATTCCGGATGAGGCAGACTTTCT GCTGGGAATGGCTACGGTGAAGAACTGCGTTTCCTACCGAGATCCTGTGAATGGAACCTGGTATATTCAG TCACTTTGCCAGAGCCTGAGGGAAAGATGTCCTCAAGGAGATGACATTCTTAGCATCCTGACTGGCGTGA ACTATGACGTGAGCAATAAAGACGACAGGAGGAACAAGGGAAAGCAGATGCCACAGCCCACCTTCACACT ACGGAAGAAGCTCTTCTTCCCTCCCTAATGATGTGTGCTCTCCACAGTTCACATGGCTTATCTGTGCACT TTTGTGTGGATGAGTCTAATTTATTTTTTAGAATTTCTTTTGCTTTTGAATTTACATTTACATAATTTTC CCTTTTCTTCCCTTTAAACCCTTCTTTGTTATGTTCCAATTTCAAATACATGGCCTCTTTTCTCATTAAC TGTTGTACACACACATACATACACACACACACACACACACACACATTTCTAAATATAACCTGTATACTAT CAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009812
• ORF Size: 1443 bp
• Insert Size: 1443
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC006737, AAH06737
• RefSeq Size: 2046
• RefSeq ORF: 1443
• Locus ID: 12370
• Gene Summary: This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode isoform (1).