Cldn11 (BC021659) Mouse Untagged Clone

CAT#: MC200822

Cldn11 (untagged) - Mouse claudin 11 (cDNA clone MGC:14055 IMAGE:4190031), (10ug)


Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cldn11
Synonyms Claudin11, Claudin-11
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC021659
CCACGCGTCCGCGCTGCACGCTGTCGCAGCAGTGCTCGCAGCCGCTCTCTCCCCATCTCGAGTAGCCCGG AGCCAGCGGCTCGCGAGGGCCAAGAGGGCAAGCCTAGGGAAGGCTCTGTCCAGGACGACACAGGGGGCAC AATCCGTGTGAGTCGAGCTGCGTGGACGTCGCTGCGGCCACCATGGTAGCCACTTGCCTTCAGGTGGTGG GTTTCGTCACGAGCTTCGTGGGTTGGATTGGCATCATCGTCACAACGTCCACCAATGACTGGGTGGTGAC CTGCAGCTACACCATCCCCACCTGCCGAAAAATGGACGAACTGGGCTCCAAGGGCCTGTGGGCTGACTGC GTCATGGCCACTGGTCTCTACCACTGCAAACCCCTGGTGGACATCCTCATCCTTCCAGGCTACGTGCAGG CTTGTAGAGCCCTCATGATTGCTGCCTCCGTTCTGGGCCTGCCCGCCATCTTGCTGCTGTTGACAGTTCT CCCCTGCATCCGAATGGGCCACGAGCCTGGAGTGGCCAAGTACAGGCGAGCCCAGCTGGCTGGGGTGCTC CTTATTCTGCTGGCTCTCTGCGCCATTGTCGCCACCATCTGGTTTCCTGTATGTGCCCACCGCGAGATCA CCATCGTGAGCTTTGGCTACTCGCTGTACGCAGGTTGGATCGGTGCTGTGATGTGCCTGGTGGGTGGCTG TGTCATCGTCTGCTGCTCCGGGGATGCACAGTCATTTGGAGAAAACCGTTTCTATTACTCTTCTGGTTCC AGCTCGCCAACGCATGCCAAGAGTGCCCATGTCTAAGAGGGCTGCTCCACTGCCCGCCGAGGTGCTGTAA ATGCTGGGCCTGGGCCCTGGGTTTGCTCGCCACAGTGGGGAGAAGCCCACTTCCCTGCCAGGCACTAAAG CCAAAGTTCTAGAAAGTATCCTGCCCCGGCATTTTGAAGTCGTAACACCCCACCCACCCACCCACCACTT CTTGGCTGCCTTAAAAGAAAGCTCTAGCTCAGTTAATGCCCACATAGTTTTCTCCTGGAGTTGCGGGCTG TGGCTGTTTGCTCTTTCCTCGGGCATTCCATTGTTGTTGATTAAAAAAATATTTTGTTTCTCTCTTAAAT TCAAATGTCTTGGGAACATTGCTGACTTGGGTGTGGATTGGGAAAGAAATAAAAGATGCTTTTCAAAGGG TTACCAACGACAGTGGAAGCCTTATAGAGACAGCTCTCTTCTCCCTTTCGGCTTAGTTTCAAGGTCACTT ATATATAAGAGATAGAAATGGATAGATTGGGAACACGGGTGGGAGGGGAACTCAGAGCTTTCCCTCCACG GGAAGCTTCTCTTTTATAAGTTGAGGGGTTGGGTGTCTTTTTTTTTTTTTAGTTTGCGATTTTACATTTT TCTGTACGTACTTTTTCAAGATTGATCATTTTTATAACCACGGGTTTCCTGAAAATTCTCAATTCACCAA TATGAAGGAAATGAACCAAGCAGACGTTAATATGCAATAAATAATAGTACGAAGATTATAACTTTAACTG ACTGCCCACGGTTTCCAGGTTTGTATGCTATAGTTTTTAATCCTATGGTTGCATATGCTTCAAATTAACA CATTTAAAAATCTTTTCTCCCCTTCTATTTCTGTCTCCATTCTGTTAGAGACCATGAAGCAGTATTGTTT AACATAAGTTGTACTGTTAAGTTTGGCTTCATGGGTGTAAACACCAATGGTCTGTCAGTGTCTAAGACTC TGGATACTGCAAGCTCCGTCCGGTGCATTTGTTCAGGTAAAATCTGTGCAATAAAATAACAAACTGTCTC CAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN BC021659
ORF Size 624 bp
Insert Size 624
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC021659, AAH21659
RefSeq Size 1848
RefSeq ORF 624
Locus ID 18417
Gene Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of CNS (central nervous system) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. The basal cell tight junctions in stria vascularis are primarily composed of this protein, and the gene-null mice suffer severe deafness. This protein is also an obligatory protein for tight junction formation and barrier integrity in the testis and the gene deficiency results in loss of the Sertoli cell epithelial phenotype in the testis. [provided by RefSeq, Aug 2010]

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