Eif4e (BC010759) Mouse Untagged Clone

CAT#: MC201074

Eif4e (untagged) - Mouse eukaryotic translation initiation factor 4E (cDNA clone MGC:18497 IMAGE:4216609), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Eif4e
• Synonyms: Eif4e-ps, eIF-4E
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC010759
  ATCTAAGATGGCGACTGTGGAACCGGAAACCACCCCTACCACTAATCCCCCACCTGCAGAAGAGGAAAAA ACAGAGTCTAATCAGGAGGTTGCTAACCCAGAGCACTATATTAAACACCCTCTACAGAACAGGTGGGCAC TCTGGTTTTTTAAAAATGATAAAAGCAAAACTTGGCAAGCAAACCTTCGATTGATCTCTAAGTTTGATAC TGTTGAAGACTTTTGGGCTCTATACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTAC TCACTTTTTAAGGACGGGATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGAGGAGGACGGTGGCTGA TCACACTGAACAAGCAGCAGAGACGGAGTGACCTCGATCGCTTCTGGCTAGAGACACTGCTGTGCCTTAT TGGAGAATCTTTCGATGACTACAGTGATGATGTGTGTGGAGCTGTTGTTAATGTTAGAGCTAAAGGTGAT AAGATAGCAATATGGACTACTGAGTGTGAAAACAGAGATGCAGTCACACACATAGGGAGGGTATACAAGG AAAGGTTAGGACTTCCTCCGAAGATAGTGATTGGTTATCAGTCCCACGCAGACACAGCTACAAAGAGCGG CTCCACCACTAAAAATAGGTTTGTTGTTTAAGAAGACACCTTCTGAGTATTCTCACAGGAGACTGCGTCA CGCAATCGAGATTGGGAGCTGAACCAAAGCCTCATCAAAGCAGAGTGGACTGCACTGAAGTTGATTCCAT CCAAGTGTTGCTAAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTCTCCTCC CCCACCCCCAATTTTTGCTAGTGTGTCCACTATCCCAATCAAAGAATTACAGTATACGTCACCCCAGAAC CCGCAGATGTGTTCCTGGCCCGCTCTGTAACAGCCGGTTAGAATTACCATGACACACACATTTGCCTTTC CACAGTATTCGAAAAAGAACTTGCATTTCTATTACCTTAGCAGGAAAGATCTGGTTTTGCTCCACTCCAT GCAGGAGCGGACTTTGCTGGTGTGAGAGTCTGAGTACAGCTTTCTAGCAACCTTCTGTTTCCTTTCACAG CATTGTCCTTGCTGTCCTCTTGCTGATGGCTGCTAGATTTAATTTATTTGCTTCCCTCCTTGATAACATT AGTGATTCTGATTTCAGTTTTTCATTTGTTTTGCTTTTGTTTTTTTCCTCGTGTAACATTGGTGAAGGAT CCAGGAATATGACAGAAAGGTGGAATAAACATTAAATTTGTGCATTCTTTGGTAATTTTTTTGTTTTTTG TAACTACAAAGCTTTGCTACAAATTTATGCATTTCATTCAAATCAGTGATCTATGTCTGTGTGATCCCTA AACATAATTGTGGACTATAAAAATGTAACACCATAATTACATTCCTAACTAGAATTAGTATGTCTGCCTT TGTATCTCTATGCTGTACTTTAACACTTTGTATTCTTAGGTTATTTTGCTTTGGTTACAATGGCTCAAGT AGAAAAGCGGTCCCATCCATATTAAGACAGTGTACAAAACTGTAAATAAAATGTGTACAGTGAATTGTCT TTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC010759
• ORF Size: 654 bp
• Insert Size: 654
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC010759, AAH10759
• RefSeq Size: 1646
• RefSeq ORF: 654
• Locus ID: 13684
• Gene Summary: This gene encodes a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. It has also been associated with autism spectrum disorders. Consistently, knockout of this gene results in increased translation of neuroligins, postsynaptic proteins linked to autism spectrum disorders. Pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]