Kdm2b (NM_013910) Mouse Untagged Clone

CAT#: MC203452

Kdm2b (untagged) - Mouse lysine (K)-specific demethylase 2B (Kdm2b), transcript variant 2, (10ug)


  "NM_013910" in other vectors (3)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Kdm2b
Synonyms Cxxc2; Fbl10; Fbxl10; Jhdm1b; PCCX2
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC057622
GGCGCGCGGTGGCGGCGGCGGCTCCCTCCTCGCCGCGCGGGAGCCCGAGCGCTAGCCAGGGTGAGCCGAG CCTGCTCCCTGCGGGCGGCGGCGGCGCTGCTCCAGCCATGTCAGCGCGCGCGAGGCTGGGCCCACCATGA GCCATGGCCATGTCCGTGAGCGCCGAGGACGACGACTATGAATCGGAGCCCGACCAGAACCGGGTGGTGG GTCGGCCTAAGGGCAAGTTGGGCCCGGCCTCAGCGGTGAAGTTGGCTGCCAACCGAACAACAGCAGGAGC TCGCAGGCGCCGGACGCGATGCCGCAAGTGCGAGGCCTGCCTGCGGACGGAGTGTGGAGAGTGCCACTTT TGCAAGGACATGAAGAAGTTTGGAGGTCCTGGGCGCATGAAGCAGAGCTGCATCATGCGGCAGTGCATCG CGCCAGTGCTGCCCCACACCGCCGTGTGCCTTGTGTGTGGCGAGGCAGGGAAGGAGGACACAGTGGAAGA GGAAGAAGGCAAGTTTAACCTCATGCTCATGGAATGCTCCATCTGCAACGAGATCATCCACCCTGGATGC CTTAAGATTAAGGAATCGGAGGGTGTGGTCAACGATGAGCTTCCCAACTGCTGGGAGTGTCCGAAGTGTA ACCATGCCGGCAAGACCGGGAAACAAAAGCGTGGCCCTGGCTTTAAGTATGCCTCCAACCTGCCTGGCTC CTTGCTCAAGGAGCAGAAGATGAACCGGGACAACAAGGAAGGGCAAGAGCCTGCCAAGCGGAGAAGTGAG TGTGAAGAGGCTCCCCGTCGGAGGTCAGACGAGCACCCCAAAAAGGTGCCTGCAGATGGCATCCTCCGCC GAAAGTCTGATGATGTGCACCTGAGGAGGAAGCGGAAATACGAGAAGCCCCAAGAGCTGAGTGGACGCAA GCGAGCCTCGTCGCTTCAAACGTCCCCCGGTTCCTCCTCTCACCTCTCGCCGAGGCCCCCTCTAGGCAGC AGTCTCAGCCCTTGGTGGAGATCCAGTCTCACTTACTTCCAGCAGCAGCTAAAACCTGGCAAAGAAGATA AGCTTTTCAGGAAAAAGCGGCGGTCCTGGAAGAACGCTGAGGATCGTCTGTCACTGGCCAACAAGCCCCT TCGGCGCTTTAAGCAGGAACCGGAGGACGATCTGCCTGAGGCACCTCCTAAGACCCGGGAGAGTGATCAG TCACGTTCCAGCTCACCCACTGCTGGTCCCAGCACTGAGGGAGCTGAAGGCCCAGAAGAGAAGAAAAAGG TGAAGATGCGCCGGAAGCGGCGACTTGTTAACAAGGAGCTGAGCAAAGAGCTAAGCAAGGAGCTCAACCA TGAGATCCAAAAGACGGAGAGCACCCTGGCTCACGAGAGCCAGCAGCCCATCAAGTCAGAGCCTGAGAGC GAGAACGACGAGCCCAAGAGGCCCTTAAGCCACTGCGAGCGCCCCCACCGCTTCAGCAAAGGGCTCAACG GCACACCTCGGGAGCTGCGGCACTCGCTGGGACCTGGCCTGCGTAGTCCACCTCGTGTTATGTCCCGGCC CCCGCCCTCTGCATCCCCACCCAAGTGCATCCAGATGGAGCGTCACGTGATCCGGCCACCGCCCATCAGC CCCCCACCTGACTCGCTGCCCCTGGATGATGGAGCAGCCCACGTCATGCATAGGGAGGTGTGGATGGCAG TCTTCAGCTACCTCAGCCACCGAGACCTGTGTGTCTGCATGCGGGTCTGCAGGACCTGGAACCGCTGGTG CTGCGATAAGCGGTTGTGGACCCGCATCGACCTGAACCGCTGCAAGTCCATCACACCCCTGATGCTGAGC GGTATCATCCGGCGACAGCCTGTCTCCCTTGACCTCAGTTGGACCAACATCTCCAAGAAGCAGCTGAGTT GGCTCATCAACCGGTTGCCTGGGCTCCGAGACTTGGTGCTGTCAGGCTGCTCATGGATCGCTGTCTCAGC CCTCTGTAGCTCCAGTTGTCCATTGCTCCGGACCCTGGATGTCCAGTGGGTAGAAGGACTAAAGGATGCC CAGATGAGGGATCTCCTGTCTCCACCCACAGACAACAGGCCAGGTCAGATGGACAATCGGAGCAAGCTCC GGAACATTGTAGAGCTGCGCCTAGCTGGCCTGGACATCACAGATGTCTCCCTGCGGCTCATTATTCGCCA TATGCCCCTGCTCTCGAAGCTCCAACTCAGTTACTGTAACCACATCAATGACCAGTCCATCAACCTGCTC ACTGCCGTCGGCACCACCACCCGAGACTCGCTGACAGAGGTCAACCTATCAGACTGTAATAAGGTAACTG ACCTGTGCCTGTCCTTCTTCAAACGCTGTGGAAATATCTGTCATATTGACCTGAGGTACTGCAAGCAAGT CACCAAGGAAGGCTGTGAGCAATTCATAGCTGAAATGTCTGTGAGTGTCCAATTTGGGCAAGTGGAAGAG AAACTCCTGCAAAAACTAAGTTAGTTCCAGGACAAGTATGTAAATATGGAGGGTTGGGGGGAATACAACC AGGAAGGGTGAAAGACTGCAAAATCAAGTGGGCCTATTATTTCCCTTTGGAATTTGAAACAAGAGACTAC AGGACACAGTTCTGTTTTGCAAATCTTGCCAAGGGGGAAGCCATTCAACCACCCATTTTGGGATGAGTGA GCCAGATGTTTTCCTTTGCTCTTTCTGCATCGTAACTGCACTGCTTTCTGGACCATTTCTAAGGCGGCCT TTAGAAGACATTCCAATTGGAAAGGAAGATGAGCTTTGGAGAAATCCTCTTAGAAGCCTAAGCTTGGTGT TTTTATCAGTAGTTTTTGTTTGGGGCACTTGTTCCTTGCAATGCTGAGGCTTCTGGCGTCAACATGGAGT GGACCACACACACACCATCTTCAGCCGTCGTTGATACATTTTGTTTAGTTGGTTTTGTTACATCTTACAT TATGCAGAACTATTTTTGTATAAATTGTTTAAAAATTATTTATGGGAGATTTGAATGCATACCAGTGTTT TTATTATTTAGATTGCCAACTGTCCTTCAGGTAGGAGAGTTAACCTGTACTATGTCAGCATAAAAAGCCC ATCTCCAGATGTGCCCAGGTGTGACAGGGGGCTATGACCTTCCACTTAAAAAGCATGTTTAACTGGATGC TGAGAGCCTACTGTGTATGTCAAGAAGCTACACAAGCATGTTGTGGATATGTGTAAAGTATAGTCCAGGT AAAACACTTTGCCAAGTTTCAATAGACTTCACCTCTCCCTCAGACTTGAGCCTTTACACTCAGGAGGGTT TGCTCCAAGCATGAGCTCTTGTATTCTACTTACATAGGTCTAATTTATACCAAGAATCAGGTAGAATAAA TGTGCCCACACCCTCTCCTTTGTCCTCCTCCTCTCAAGTGTTCAGTTCTCACTTTAGTTGGTAAGTTCTG CATCCCTTGTTGTTTGGTGGTGTTTCCTAACCTTTCCCTGATGCAGTTTGACCTTTGTTGGATTTATATA AACAATTGTACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites AscI-NotI     
ACCN NM_013910
ORF Size 2331 bp
Insert Size 2331
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC057622, AAH57622
RefSeq Size 3545
RefSeq ORF 2331
Locus ID 30841
Gene Summary The protein encoded by this gene is a H3K36-specific histone demethylase, which contains an N-terminal jumonji C domain, a CxxC zinc finger domain, a plant homeodomain finger, an F-box, and eight leucine-rich repeats. Amongst its demonstrated functions, this protein plays roles in the suppression of premature cellular senescence, leukemia maintenance and development, maintenance of mouse embryonic stem cell pluripotency, and induced pluripotent stem cell generation. Mice homozygous for a targeted deletion of the zinc finger domain display embryonic lethality with development ceasing at approximately 7 to 8 days post coitum, demonstrating an essential role in early development. A pseudogene of this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Transcript Variant: This variant (2) lacks exons in the 5' UTR and 5' coding region and uses an alternate 5' terminal exon compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.

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