Fzd1 (NM_021457) Mouse Untagged Clone

CAT#: MC203642

Fzd1 (untagged) - Mouse frizzled homolog 1 (Drosophila) (Fzd1), (10ug)


  "NM_021457" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Fzd1
Synonyms AW227548; FZ-1; Fz1
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC053010
GCGGCGGAGAAGGAGGAGGCGGAGGCGCAGGGGGGACCCAGGGCGGCTAGGCTGCCGAGAGTTGGGCGCT CCTCTGCCCGGCTGCGACCACTAACGCGGCGCCGCCTGACAAGAGCCACAGCCTGCCGCGGGCCAGGGAA GAGGGACGCGACCCCGGCGCGCCTGGACCACTCTTGCTCTCCTCGCCGCCCGCGCTTCATGAACCGCAAG TTTCCGCGGCGGCGGCGGCGGCTGCGGGACGCGGAGCAGAATCCCGGGGAGCGGGCAGAGAGCGGCCGCA CCCCGACGGAGGGCACGGGCGACCAGCTCTCCCGGATCACAGTGGGAGCCACCACCCGCCGCGCCGCTGC CCGTCCCAGTCAATCCGCGCCGAGGAGGGAGCCGAAAAAGTATGGCTGAGGAGGCGGCGCCTAGCGAGTC CCGGGCCGCCGGCCGGCTGAGCTTGGAACTTTGTGCCGAAGCACTCCCGGGCCGGCGGGAGGAGGTGGGG CACGAGGACACGGCCAGCCACCGCCGCCCCCGGGCTGATCCCCGGCGTTGGGCTAGCGGGCTGCTGCTGC TGCTTTGGTTGCTGGAGGCTCCTCTGCTTTTGGGGGTCCGAGCGCAGGCGGCGGGCCAGGTATCCGGGCC GGGCCAGCAAGCCCCGCCGCCGCCCCAGCCCCAGCAGAGCGGGCAGCAGTACAACGGCGAACGGGGCATC TCCATCCCGGACCACGGCTACTGCCAGCCCATCTCCATCCCGCTGTGCACGGACATCGCGTACAACCAGA CCATCATGCCCAACCTGCTGGGCCACACGAATCAGGAGGACGCCGGTCTGGAGGTGCACCAGTTCTACCC TCTGGTGAAGGTGCAGTGCTCCGCCGAGCTCAAGTTCTTCCTGTGCTCCATGTACGCGCCTGTGTGCACC GTACTGGAGCAGGCGCTACCGCCCTGCCGCTCCCTGTGCGAGCGCGCACGCCAGGGCTGCGAGGCGCTCA TGAACAAGTTCGGCTTCCAGTGGCCAGACACACTCAAGTGCGAGAAGTTCCCGGTGCACGGCGCAGGAGA GCTGTGCGTGGGCCAGAACACGTCCGACAAAGGCACCCCAACTCCCTCCTTGCTACCAGAGTTCTGGACC AGTAATCCGCAGCACGGCGGCGGTGGTTACCGCGGCGGCTACCCGGGGGGTGCCGGGACGGTGGAGCGGG GAAAGTTCTCCTGCCCGCGCGCCCTCAGGGTGCCCTCCTACCTCAACTACCACTTTCTGGGGGAGAAGGA CTGCGGCGCACCCTGCGAACCCACCAAGGTTTACGGGCTCATGTACTTCGGGCCAGAGGAGCTGCGCTTC TCGCGCACCTGGATAGGCATCTGGTCCGTGCTGTGCTGCGCCTCCACGCTCTTCACGGTGCTCACGTACC TAGTGGACATGCGGCGCTTCAGCTACCCGGAACGGCCCATCATTTTCCTGTCCGGCTGTTACACAGCGGT GGCGGTGGCCTACATCGCTGGCTTTCTGTTGGAGGACCGGGTGGTGTGCAACGACAAGTTTGCAGAGGAC GGGGCGCGCACGGTGGCGCAGGGCACTAAGAAAGAAGGCTGCACTATACTCTTTATGATGCTCTACTTCT TCAGCATGGCCAGCTCCATCTGGTGGGTGATCCTGTCCCTCACCTGGTTCCTGGCAGCCGGCATGAAGTG GGGCCACGAAGCCATCGAGGCCAACTCACAGTATTTCCATTTAGCCGCCTGGGCTGTGCCAGCCATCAAA ACTATAACCATCTTGGCGTTGGGCCAGGTGGATGGCGACGTACTGAGCGGAGTGTGTTTTGTGGGGCTCA ACAACGTGGACGCACTGCGTGGCTTTGTGCTGGCGCCTCTCTTCGTTTATCTGTTCATTGGCACTTCTTT CCTGCTGGCCGGTTTCGTGTCACTCTTCCGCATCCGCACCATCATGAAGCATGACGGCACCAAGACAGAG AAGCTGGAGAAGCTCATGGTGCGCATCGGAGTCTTCAGTGTCCTCTACACTGTGCCGGCCACCATCGTCA TCGCCTGCTACTTCTATGAACAGGCCTTTCGGGACCAGTGGGAGCGCAGCTGGGTGGCCCAGAGCTGCAA GAGTTATGCCATCCCTTGCCCTCACCTCCAGGGAGGTGGAGGAGTCCCACCACACCCGCCCATGAGCCCA GACTTTACAGTCTTCATGATCAAGTATCTCATGACGCTGATTGTGGGCATCACATCGGGCTTCTGGATCT GGTCCGGCAAGACACTGAATTCCTGGAGGAAGTTCTACACGAGGCTTACCAACAGCAAACAGGGGGAGAC TACCGTCTGAAACCCAGACTCTTACCTTACCCTTTTTTGGCCTGATCCTAGCCATCGCCTGGAAGCTGGC CCCAAGGAATTCCTGCCAAGCCTGGCCACTCCAGGCTTCCTCGCCAGCCACTGACTTTTGCAGGCCCCTT TCCCAACAAACAGCACAGGTTCTGCAAAAGCTTCCGTCCCTGGGGTAAAGGAACGAGAGGGCCCAACTGA TCGAGGTGTATGTGTATGTGCGTGTGGACCGATCTCTCTAGCCCTCTCTGATACCAGGATTGTACGCTTT TATGATTGTAAATAGCCTGTGTAAGATTTTTGTACGTATATTTGTATTTAAAGACTATCGAACACGCAGT TTTTTTTTCTTTTTAAAAATGTTTAATTATTTAGGGCAATTTACGTATTTGGAGCTTTTCTCACTTGCCC TTTTCTGCAGATTGCAGAGGAGGTAAAACAGAGCACACTTGACTAAGTGCTTTGCCCTGTGCCCTCATCT TTGTCAAGGGAGCATGGGCCTGCCTCTCCAGGGTCATTTCCTTCAGCATCTCCCGCCCCTCCCCTTCCTT GCTTGCAGTGGGAAATTTTAAGGTGCAGAACTCTGTAAAGCTTCCAGATCCCGAGGTGGGCCCCGCCCAT TCCAGATCCTCCCCTTTTCAGCGGTAGAGTGTGGATGGCTGTCCCTGTGGCTTCCTGATGCTGCTTATTT GAGATCCACCTTCCAGCTTTATTAGAGGACCCCAGTATGGGCTCTGCCAGTTGACCCAGCCTCCCTGTAC CCCGGTGTCCCTTGCCCAGTGTCTTTCTCCTTGCACCTAAGTTGTTCAGAGGGAGTGCAGTAACCGACCG ATAGCGAACTTTGGAGAGTCTGACTTTTTATGGATGAGCTCATTTTTACTCTCTAGTATCTGGAACTTGC TCTGGGTCTGGTCATCATCATGGAAAGAGCAGCAAGCTTTGTGGGTTGGGAGAGGCTAAAGAGAGAGGTT ATAAAACATTAGTTCTAATTGCATTCTGATGTCTGGCAACCTACTTTCTTCCCCCTGTGATGCTGCCTGC TTCTAGATTTTACCCTTCTATGAAATGCAGACCTCGAGGTTGCCTGGGAAGCTTGGTGAAGGAATGGTTT ACCTTCCTTAACAGGATAGTAGAACATACACAGAGTATGGAAACCTAAGGAGATTTCAGTGAAGTGGAGT TACTCCAAGTGAAACGCTGTTTTCTGGTTTTAGCCAAACTGCAATTAGATGTGTCTTTGCAATCTAAAAG TTGTACACAATCAACAATACACTTTGCTTACTCCTCAGCAGCACATTCTGAGGGAGAAACAGTCACACCC CCGCAGAAAGCCTGGTTGGACTTCCGAAGACAGAGGCGGTGGACTGACGGATGGGTGAGAGAGACAAACA CGACCTAGGCATGCATGCTGAAGGGGAAGTGTGTCCATTCCTACTGCATCCCATCTTGTGTGCTCCTGTC TGGATTTACGGCAGTGTGTCAAATGTAAATCTCTCAAAGCCATTTAAAAATACTCACTTTAGTTATGGAT GAAGAAGAGGAGAAAAGCAGTCCTCCTGATTGTAGTGTTTAAACCTTAAGAGTTTATCACAAATGCCGAT ACATACATAGGACCTAAATTTATCTATGTCTGTCATACCCTAAAATGACATTGGTTTTTGGATTTGGTAT GCATTATTATTGTTATTATTGTTATTATTATTCTCACCACCATGAGATCATCTATATTTATAGAGGAATA GAAGTTTATATATATAAAATGCCATATTTTTAATTTCGCAAATAAAAAAATGAAAGTTTTGTACAAAATT ACAAAAAAAAAAAAAAAAAA
Restriction Sites AscI-NotI     
ACCN NM_021457
ORF Size 1929 bp
Insert Size 1929
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC053010, AAH53010
RefSeq Size 4150
RefSeq ORF 1929
Locus ID 14362
Gene Summary Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. [UniProtKB/Swiss-Prot Function]

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